chowwhite (run-chowwhite-varysize.xml)
Chow and White (1996), Biophys J. Showing spontaneous spiking with varying numbers of channels
Total CPU time 55.71 seconds; at 12:36:07 Thu 24 Sep 2009
Compartments | Stochastic channels / cpmts | Continuous channels / cpmts | Non Gated channels / cpmts | time/ms | timestep/ms | p0:r | CPU Time / s |
1 | 780 / 1 | 0 / 0 | 3000 / 1 | 1.00e+03 | 0.02 | 0.89206 | 1.74 |
1 | 3900 / 1 | 0 / 0 | 15000 / 1 | 1.00e+03 | 0.02 | 1.99471 | 7.83 |
1 | 7800 / 1 | 0 / 0 | 29999 / 1 | 1.00e+03 | 0.02 | 2.8209 | 15.4 |
1 | 15599 / 1 | 0 / 0 | 60000 / 1 | 1.00e+03 | 0.02 | 3.98942 | 30.7 |
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Morphology: cell




Predefined views
whole

start

end

All files
Model
Archive file of the complete model: chowwhite.jarrun-chowwhite-varysize.xml
<PSICSRun timeStep="0.02ms" runTime="1000ms" startPotential="-65mV" morphology="cell" environment="environment" properties="membrane" access="recording" stochThreshold="1000000" oneByOne="true" quickChannels="true"> <RunSet vary="p0:r" values="[0.89206, 1.99471, 2.8209, 3.98942]um" filepattern="radius-$"/> <info>Chow and White (1996), Biophys J. Showing spontaneous spiking with varying numbers of channels</info> <ViewConfig> <LineGraph width="500" height="400"> <XAxis min="0" max="250" label="time / ms"/> <YAxis min="-80" max="60" label="potential / mV"/> <LineSet file="radius-0.89206.txt" color="orange"/> <LineSet file="radius-1.99471.txt" color="blue"/> <LineSet file="radius-2.8209.txt" color="green"/> <LineSet file="radius-3.98942.txt" color="yellow"/> <!-- <LineSet file="radius-5.64189.txt" color="red"/> --> <View id="whole" xmin="-10." xmax="10000." ymin="-100." ymax="80."/> <View id="start" xmin="0." xmax="500." ymin="-100." ymax="80."/> <View id="end" xmin="500." xmax="600." ymin="-100." ymax="80."/> </LineGraph> </ViewConfig> </PSICSRun>
cell.xml
<CellMorphology id="cell"> <Point id="p0" x="0" y="0" z="0" r="5.4"/> </CellMorphology>
membrane.xml
<CellProperties id="membrane" cytoplasmResistivity="100ohm_cm" membraneCapacitance="1uF_per_cm2"> <ChannelPopulation channel="NaHH" density="60per_um2"/> <ChannelPopulation channel="KHH" density="18per_um2"/> <ChannelPopulation channel="Leak" density="300per_um2"/> </CellProperties>
environment.xml
<CellEnvironment id="environment"> <Ion id="Na" name="Sodium" reversalPotential="50mV"/> <Ion id="K" name="Potassium" reversalPotential="-77mV"/> <Ion id="LEAK" name="Non-specific leak" reversalPotential="-54.4mV"/> </CellEnvironment>
recording.xml
<Access id="recording"> <VoltageRecorder at="p0" lineColor="blue"/> </Access>
NaHH.xml
<KSChannel id="NaHH" permeantIon="Na" gSingle="20pS"> <KSComplex id="m" instances="3"> <ClosedState id="c"/> <OpenState id="o"/> <ExpLinearTransition from="c" to="o" rate="1per_ms" midpoint ="-40mV" scale="10mV"/> <ExpTransition from="o" to = "c" rate="4per_ms" midpoint="-65mV" scale="-18mV"/> </KSComplex> <KSComplex id="h"> <ClosedState id="c"/> <OpenState id="o"/> <ExpTransition from="c" to="o" rate="0.07per_ms" midpoint="-65mV" scale="-20mV"/> <SigmoidTransition from="o" to="c" rate="1per_ms" midpoint="-35mV" scale="10mV"/> </KSComplex> </KSChannel>
KHH.xml
<KSChannel id="KHH" permeantIon="K" gSingle="20pS"> <KSComplex id="n" instances="4"> <ClosedState id="c"/> <OpenState id="o"/> <ExpLinearTransition from="c" to="o" rate="0.1per_ms" midpoint ="-55mV" scale="10mV"/> <ExpTransition from="o" to = "c" rate="0.125per_ms" midpoint="-65mV" scale="-80mV"/> </KSComplex> </KSChannel>
Leak.xml
<KSChannel id="Leak" gSingle="0.01pS" permeantIon="LEAK"> <OpenState id="o1"/> </KSChannel>