cwvclamp (rcwvc.xml)
Chow and White (1996), Biophys J
Total CPU time 1.640 seconds; at 10:36:02 Thu 24 Sep 2009
Compartments | Stochastic channels / cpmts | Continuous channels / cpmts | Non Gated channels / cpmts | time/ms | timestep/ms | stochThreshold | CPU Time / s |
1 | 780 / 1 | 0 / 0 | 3000 / 1 | 1.00e+03 | 0.01 | 1000000000 | 1.41 |
1 | 0 / 0 | 780 / 1 | 3000 / 1 | 1.00e+03 | 0.01 | 0 | 0.230 |
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Morphology: cell


Predefined views
whole

mean= 0.08880, sd= 4.758e-08 st-0.txt, line 2
mean= 0.08730, sd= 0.04223 st-1000000000.txt, line 2
mean= 0.08730, sd= 0.04223 st-1000000000.txt, line 2
All files
Model | Preprocessed | Outupt data | Reference data etc |
rcwvc.xml cell.xml membrane.xml environment.xml record-voltageclamp.xml NaHH.xml KHH.xml Leak.xml |
st-1000000000.ppp st-0.ppp |
log.txt st-1000000000.sum st-0.sum st-1000000000.dat st-1000000000.txt st-0.dat st-0.txt |
whole.txt |
Model
Archive file of the complete model: cwvclamp.jarrcwvc.xml
<PSICSRun timeStep="0.01ms" runTime="1s" startPotential="-65mV" morphology="cell" environment="environment" properties="membrane" access="record-voltageclamp" stochThreshold="1000000" quickChannels="true" repeats="1"> <RunSet vary="stochThreshold" values="[1000000000 0]" filepattern="st-$"/> <info>Chow and White (1996), Biophys J</info> <ViewConfig> <LineGraph width="1000" height="400"> <XAxis min="0" max="100" label="time / ms"/> <YAxis min="-5" max="5" label=""/> <LineSet file="st-0.txt" color="green" show="2"> <Stats xmin="100ms"/> </LineSet> <LineSet file="st-1000000000.txt" color="yellow" show="2"> <Stats xmin="100ms"/> </LineSet> <View id="whole" xmin="-10." xmax="400." ymin="-0." ymax="0.3"/> </LineGraph> </ViewConfig> </PSICSRun>
cell.xml
<CellMorphology id="cell"> <Point id="p0" x="0" y="0" z="0" r="0.89206"/> </CellMorphology>
membrane.xml
<CellProperties id="membrane" cytoplasmResistivity="100ohm_cm" membraneCapacitance="1uF_per_cm2"> <ChannelPopulation channel="NaHH" density="60per_um2"/> <ChannelPopulation channel="KHH" density="18per_um2"/> <ChannelPopulation channel="Leak" density="300per_um2"/> </CellProperties>
environment.xml
<CellEnvironment id="environment"> <Ion id="Na" name="Sodium" reversalPotential="50mV"/> <Ion id="K" name="Potassium" reversalPotential="-77mV"/> <Ion id="LEAK" name="Non-specific leak" reversalPotential="-54.4mV"/> </CellEnvironment>
record-voltageclamp.xml
<Access id="record-voltageclamp" recordClamps="true"> <VoltageClamp at="p0" hold="-60mV" record="false"/> <!-- <SmartRecorder at="p0" record="current" channel="NaHH"/> <SmartRecorder at="p0" record="current" channel="KHH"/> <SmartRecorder at="p0" record="conductance" channel="NaHH"/> --> <SmartRecorder at="p0" record="conductance" channel="KHH"/> </Access>
NaHH.xml
<KSChannel id="NaHH" permeantIon="Na" gSingle="20pS"> <KSComplex id="m" instances="3"> <ClosedState id="c"/> <OpenState id="o"/> <ExpLinearTransition from="c" to="o" rate="1per_ms" midpoint ="-40mV" scale="10mV"/> <ExpTransition from="o" to = "c" rate="4per_ms" midpoint="-65mV" scale="-18mV"/> </KSComplex> <KSComplex id="h"> <ClosedState id="c"/> <OpenState id="o"/> <ExpTransition from="c" to="o" rate="0.07per_ms" midpoint="-65mV" scale="-20mV"/> <SigmoidTransition from="o" to="c" rate="1per_ms" midpoint="-35mV" scale="10mV"/> </KSComplex> </KSChannel>
KHH.xml
<KSChannel id="KHH" permeantIon="K" gSingle="20pS"> <KSComplex id="n" instances="4"> <ClosedState id="c"/> <OpenState id="o"/> <ExpLinearTransition from="c" to="o" rate="0.1per_ms" midpoint ="-55mV" scale="10mV"/> <ExpTransition from="o" to = "c" rate="0.125per_ms" midpoint="-65mV" scale="-80mV"/> </KSComplex> </KSChannel>
Leak.xml
<KSChannel id="Leak" gSingle="0.01pS" permeantIon="LEAK"> <OpenState id="o1"/> </KSChannel>