mean-variance-iv-stoch
rallpack1
rallpack3
rallpack2
rallpack3-stoch
rallpack3-stoch2
stimtest
chowwhite
multirec
smartrec
mean-variance
mean-variance-iv-det
migliore-1a
mainen
cell-loc
raster
cianmar30
psd
migliore-pass
functest
stochdet
ivconv
vcsteps
synapses
cwvclamp
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minor

mean-variance-iv-det (runivdet.xml)

I-V curves for the same model as is used for mean variance analysis.

Total CPU time 0.4900 seconds; at 11:23:36 Mon 14 Apr 2008

CompartmentsStochastic
channels / cpmts
Continuous
channels / cpmts
Non Gated
channels / cpmts
time/mstimestep/msnapop:densityCPU Time / s
10 / 05 / 10 / 040.00.010.4 0.0900
10 / 025 / 10 / 040.00.012 0.100
10 / 050 / 10 / 040.00.014 0.100
10 / 0101 / 10 / 040.00.018 0.100
10 / 0201 / 10 / 040.00.0116 0.100

Morphology: cell

 

 

 

 

 

Predefined views

0.4

2

4

8

16

All files

ModelPreprocessedOutupt dataReference data etc
runivdet.xml
cell.xml
membrane.xml
environment.xml
recording-iv.xml
na1.xml
out-0.4.ppp
out-2.ppp
out-4.ppp
out-8.ppp
out-16.ppp
log.txt
out-0.4.sum
out-2.sum
out-4.sum
out-8.sum
out-16.sum
out-0.4.dat
out-0.4.txt
out-2.dat
out-2.txt
out-4.dat
out-4.txt
out-8.dat
out-8.txt
out-16.dat
out-16.txt

Model

Archive file of the complete model: mean-variance-iv-det.jar

runivdet.xml

<PSICSRun timeStep="0.01ms" runTime="40ms" startPotential="-80mV"
	morphology="cell"
	environment="environment"
	properties="membrane"
	access="recording-iv"
	stochThreshold="0">

	<StructureDiscretization baseElementSize="3um"/>

<RunSet vary="napop:density" values="[0.4, 2, 4, 8, 16]per_um2"
                filepattern="out-$">
 		<CommandSet vary="vstep:to" values="[-60, -40, -30, -20, -10, 0, 10, 20, 30, 40]mV"/>
	</RunSet>



<About>
  	I-V curves for the same model as is used for mean variance analysis.
 </About>



	<ViewConfig>
		<LineGraph width="500" height="400">
		<XAxis min="0" max="250" label="time / ms"/>
		<YAxis min="-80" max="60" label="current / nA"/>
		<LineSet file="out-0.4.txt" color="pink"/>
		 <View id="0.4" xmin="0." xmax="40." ymin="-25." ymax="5."/>
		</LineGraph>
	</ViewConfig>


	<ViewConfig>
		<LineGraph width="500" height="400">
		<XAxis min="0" max="250" label="time / ms"/>
		<YAxis min="-80" max="60" label="current / nA"/>
		<LineSet file="out-2.txt" color="red"/>
		 <View id="2" xmin="0." xmax="40." ymin="-100." ymax="10."/>
		</LineGraph>
	</ViewConfig>


	<ViewConfig>
		<LineGraph width="500" height="400">
		<XAxis min="0" max="250" label="time / ms"/>
		<YAxis min="-80" max="60" label="current / nA"/>
		<LineSet file="out-4.txt" color="orange"/>
		 <View id="4" xmin="0." xmax="40." ymin="-180." ymax="10."/>
		</LineGraph>
	</ViewConfig>


	<ViewConfig>
		<LineGraph width="500" height="400">
		<XAxis min="0" max="250" label="time / ms"/>
		<YAxis min="-80" max="60" label="current / nA"/>
		<LineSet file="out-8.txt" color="blue"/>
		 <View id="8" xmin="0." xmax="40." ymin="-300." ymax="10."/>
		</LineGraph>
	</ViewConfig>


	<ViewConfig>
		<LineGraph width="500" height="400">
		<XAxis min="0" max="250" label="time / ms"/>
		<YAxis min="-80" max="60" label="current / nA"/>
		<LineSet file="out-16.txt" color="green"/>
		 <View id="16" xmin="0." xmax="40." ymin="-600." ymax="20."/>
		</LineGraph>
	</ViewConfig>
</PSICSRun>

cell.xml

<CellMorphology id="cell">

    <Point id="p0" x="0" y="0" z="0" r="1."/>

</CellMorphology>

membrane.xml

<CellProperties id="membrane"
      cytoplasmResistivity="100ohm_cm"
      membraneCapacitance="1uF_per_cm2">

	<ChannelPopulation id="napop" channel="na1" density="16per_um2"/>


</CellProperties>

environment.xml

<CellEnvironment id="environment">
	<Ion id="Na" name="Sodium" reversalPotential="80mV"/>
	<Ion id="K" name="Potassium" reversalPotential="-80mV"/>
</CellEnvironment>

recording-iv.xml

<Access id="recording-iv" saveInterval="0.01ms">

	<VoltageClamp at="p0" lineColor="red" hold="-80.0mV">
		<VoltagePulse id="vstep" start="5ms" to="0mV"
			      duration="20ms"/>

	</VoltageClamp>

</Access>

na1.xml

<KSChannel id="na1" gSingle="30pS" permeantIon="Na">
	<ClosedState id="c1"/>
	<OpenState id="o1"/>
	<ClosedState id="c2"/>

	<VHalfTransition from="c1" to="o1" vHalf = "-35mV" z="4.5e" gamma="0.8" tau="0.55ms" tauMin="0.1ms"/>

	<VHalfTransition from="o1" to="c2" vHalf = "-70mV" z="1.1e" gamma="0.90" tau="12.0ms" tauMin="1.5ms"/>

</KSChannel>